4F-MPH Crystalline Powder and Rocks
Overview
4F-MPH Crystalline Powder and Rocks or 4-Fluoromethylphenidate (commonly known as 4F-MPH) is a novel synthetic stimulant of the phenidate class. It is a closely related structural analog of the commonly prescribed ADHD drug methylphenidate (known by the brand-names Ritalin and Concerta).
The two substances are believed to have very similar pharmacological mechanisms as monoamine reuptake inhibitors but have been reported to display distinctive subjective effects.
4F-MPH has an extremely short history and has yet to be documented. It was initially developed as a replacement for ethylphenidate. Learn More
WE in no way condoned Vivo experimentation here at FXchemlabs. We explicitly ban the use of Vivo experimentation whether on Humans or veterinary experimentation
Chemistry
4F-MPH is a synthetic molecule of the substituted phenethylamine and substituted phenidate classes, and a fluorinated analog of methylphenidate. It contains a phenethylamine core featuring a phenyl ring bound to an amino -NH2 group through an ethyl chain. It is structurally similar to amphetamine, featuring a substitution at Rα which is incorporated into a piperidine ring ending at the terminal amine of the phenethylamine chain. Additionally, it contains a methyl acetate bound to Rβ or its structure. 4F-MPH is structurally identical to methylphenidate with the exception of a single fluorine atom bound to the four position on the phenethylamine core.
With respect to nomenclature, the methyl- in methylphenidate regards the side chain of one carbon atom, while phen- indicates the phenyl ring. Id- is contracted from a piperidine ring, and -ate indicates the acetate group containing the oxygen atoms. Like its parent molecule, 4F-MPH is a chiral compound, presumably produced as a racemic mixture.
Of note is the scientific finding that amphetamine analogs containing fluorine, chlorine, bromine and methyl groups are typically stronger than those without. Learn More
4F-MPH Crystalline Powder and Rocks Pharmacology
4F-MPH is thought to act primarily as a dopamine and norepinephrine reuptake inhibitor, meaning it effectively boosts the levels of dopamine and norepinephrine neurotransmitters in the brain by binding to and partially blocking the transporter proteins that normally clear these catecholamines from the synaptic cleft. This allows dopamine and norepinephrine to accumulate within the reward pathways in the brain, resulting in stimulating and euphoric effects.
According to a recent study, 4-FMPH is about as effective as methylphenidate as a norepinephrine reuptake inhibitor (NRI), but is approximately three times as effective at inhibiting the reuptake of dopamine as its parent compound. Learn More
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