Bromazolam (8-Bromo-1-Methyl-6-Phenyl-4H-[1,2,4]Triazolo[4,3-a][1,4]Benzodiazepine)
Premium Benzodiazepine Analog for Pharmacological & Forensic Research
Bromazolam is a triazolobenzodiazepine derivative developed for scientific, pharmacological, and analytical research. Structurally similar to alprazolam and flualprazolam, this compound exhibits high affinity for GABA-A receptors, making it a valuable tool for studying CNS depressant pharmacology, receptor binding, and structure-activity relationships (SAR).
Scientific Overview
Bromazolam functions as a potent GABA-A receptor positive allosteric modulator, enhancing the inhibitory effects of gamma-aminobutyric acid (GABA) in the central nervous system. Researchers utilize it for controlled studies into:
Anxiolytic, hypnotic, and sedative pharmacodynamics
⚙️ Benzodiazepine receptor binding and modulation
Comparative potency within the triazolobenzodiazepine class
Tolerance and dependency model development
Its bromine substitution at the 8-position contributes to distinct binding kinetics and potency, offering researchers valuable insight into chemical modifications and receptor response correlations.
⚠️ Safety & Handling Notice
Bromazolam is a highly potent CNS depressant research compound. It must only be handled by qualified professionals in certified laboratory environments under strict safety and regulatory compliance.
Potential Hazards Include:
❗ Sedation, drowsiness, and motor impairment
❗ Respiratory depression and CNS suppression
❗ Potential for tolerance, dependence, and withdrawal effects
STRICTLY FOR RESEARCH USE ONLY
-
Not for human or animal consumption
-
Not for medical, therapeutic, or recreational use
-
Intended solely for analytical, pharmacological, or forensic studies
Proper PPE, fume handling, and secure storage protocols are mandatory when working with this substance.
Key Features
✅ High-purity triazolobenzodiazepine analog
✅ Valuable for GABA-A receptor and CNS activity studies
✅ Applicable in forensic, toxicological, and pharmacological research
Bromazolam remains a cornerstone compound for researchers investigating benzodiazepine receptor modulation, sedative pharmacology, and CNS depressant behavior. ⚗️
